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Comparative Genomics - 9780849392160

Un libro in lingua di Brown James R. (EDT) edito da Taylor & Francis, 2007

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During his career in pharmaceutical research and development, Brown (GlaxoSmithKline, Collegeville, PA) has witnessed the expansion of the viewing of comparative genomics as a venture confined to understanding pathogens and the "holy trinity species" of medical research (mouse, rat, and human) to the genomes of reptiles, birds and other mammalian species as models for human disease. Eighteen chapters, divided between basic and applied research, show cross-fertilization in the field. Initial chapters review challenges and methodological advances in DNA sequencing technology accelerating the generation of new genomic data, and the somewhat controversial "deep" evolution study of species. Applied chapters address the utility of comparative genomics in drug discovery research, treatment of infectious agents and diseases such as cancer, and improvement of crops. Annotation ©2008 Book News, Inc., Portland, OR (booknews.com)

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