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Cell Culture and Upstream Processing - 9780415399692

Un libro in lingua di Butler Michael (EDT) edito da Taylor & Francis, 2007

  • € 118.00
  • Il prezzo è variabile in funzione del cambio della valuta d’origine

Drawn from those presented at highly acclaimed conferences on animal cell technology and protein expression, these papers describe to professionals and students how to improve yields and optimize the cell culture production process for pharmaceuticals by focusing on safety, quality, economics, operability and productivity issues. The nine papers cover mammalian cell culture in cell line development and culture strategies that improve yields, the use of DNA insulator elements and scaffold/matrix-attached regions for enhanced recombinant protein expression, targeted gene insertion to enhance production from cell lines, recombinant human IgG production from myeloma and Chinese hamster ovary cells, cell culture media development with customized components and supplements that are animal-free, post-translation modification of recombinant antibody proteins, metabolic engineering to control glycosylation, humanization of N-glycosylation pathways in yeast, and a matter of perspective on perfusion of fed-batch processing. Annotation ©2007 Book News, Inc., Portland, OR (booknews.com)

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