Drug Discovery and Development - 9780471398479
Un libro in lingua di Chorghade Mukund S. (EDT) edito da John Wiley & Sons Inc, 2007
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From first principles to real-world applications-here is the first comprehensive guide to drug discovery and development
Modern drug discovery and development require the collaborative efforts of specialists in a broadarray of scientific, technical, and business disciplines-from biochemistry to molecular biology, organic chemistry to medicinal chemistry, pharmacology to marketing. Yet surprisingly, until now, there were no authoritative references offering a complete, fully integrated picture of the process.
The only comprehensive guide of its kind, this groundbreaking two-volume resource provides an overview of the entire sequence of operations involved in drug discovery and develop-?ment-from initial conceptualization to commercialization to clinicians and medical practitioners.
Volume 1: Drug Discovery describes all the steps in the discovery process, including conceptualizing a drug, creating a library of candidates for testing, screening candidates for in vitro and in vivo activity, conducting and analyzing the results of clinical trials, and modifying a drug as necessary.
Volume 2: Drug Development delves into the nitty-gritty details of optimizing the synthetic route, drug manufacturing, outsourcing, and marketing-including drug coloring and delivery methods.
Featuring contributions from a world-class team of experts, Drug Discovery and Development:
- Features fascinating case studies, including the discovery and development of erythromycin analogs, Tagamet, and Ultiva (remifentanil)
- Discusses the discovery of medications for bacterial infections, Parkinson's disease, psoriasis, peptic ulcers, atopic dermatitis, asthma, and cancer
- Includes chapters on combinatorial chemistry, molecular biology-based drug discovery, genomics, and chemogenomics
Drug Discovery and Development is an indispensable working resource for industrial chemists, biologists, biochemists, and executives who work in the pharmaceutical industry.
Informazioni bibliografiche
- Titolo del Libro in lingua: Drug Discovery and Development
- Sottotitolo: Drug Development
- Lingua: English
- Autore: Chorghade Mukund S. (EDT)
- Editore: John Wiley & Sons Inc
- Collana: John Wiley & Sons Inc (Hardcover)
- Data di Pubblicazione: 31 Agosto '07
- Genere: MEDICAL
- Argomenti : Drug development Drug Design Chemistry, Pharmaceutical methods
- Pagine: 381
- Dimensioni mm: 260 x 171 x 19
- ISBN-10: 0471398470
- EAN-13: 9780471398479