Linkage Disequilibrium And Association Mapping - 9781588296696
Un libro in lingua di Collins Andrew R. edito da Springer Verlag, 2007
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Researchers and clinicians alike are finding it difficult to keep up with all the advances in mapping disease genes. This synthesis offers a brief technical overview and history so readers can locate their own current level of knowledge in this rapidly changing fields, then contributors of the remaining papers describe linkage disequilibrium maps (LDMAPs) and location databases, construction of high-resolution LDMAPs for the human genome, linkage disequilibrium as a tool for detecting signatures of natural selections, the genetic basis of complex traits, LDMAPs as tools in studying complex disease genes, LDMAPs and disease-association mapping, coalescent methods for fine-scale disease-gene mapping, family-based linkage disequilibrium tests using general pedigrees, and association studies using familial cases as an efficient strategy for identifying low-penetrating disease alleles. Annotation ©2007 Book News, Inc., Portland, OR (booknews.com)
Informazioni bibliografiche
- Titolo del Libro in lingua: Linkage Disequilibrium And Association Mapping
- Sottotitolo: Analysis And Applications
- Lingua: English
- Autore: Collins Andrew R.
- Editore: Springer Verlag
- Collana: Springer Verlag (Hardcover)
- Data di Pubblicazione: 30 Dicembre '07
- Genere: SCIENCE
- Argomenti : Genomics Statistical methods Gene mapping Linkage Disequilibrium
- Pagine: 255
- Dimensioni mm: 234 x 158 x 25
- ISBN-10: 1588296695
- EAN-13: 9781588296696