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P53 Protocols - 9781588291066

Un libro in lingua di Deb Sumitra (EDT) Deb Swati Palit (EDT) edito da Springer Verlag, 2003

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This laboratory manual describes techniques for studying the diverse properties of p53 and related proteins, and delineating the function of proteins that may serve as tumor suppressors or growth suppressors. Following the style already established by other books in the series, each chapter provides an introductory background, materials list, step-by-step instructions, and troubleshooting notes for performing a specific procedure. Topics of the 18 chapters include generation and characterization of p53 mutant mice, identification of p53 target genes by fluorescent differential display, and flow cytometric analysis of MDM2-mediated growth arrest. Annotation (c) Book News, Inc., Portland, OR (booknews.com)

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