A Handbook for Dna-encoded Chemistry - 9781118487686
Un libro in lingua di Goodnow Robert A. Jr. edito da John Wiley & Sons Inc, 2014
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This book comprehensively describes the development and practice of DNA-encoded library synthesis technology. Together, the chapters detail an approach to drug discovery that offers an attractive addition to the portfolio of existing hit generation technologies such as high-throughput screening, structure-based drug discovery and fragment-based screening. The book:
- Provides a valuable guide for understanding and applying DNA-encoded combinatorial chemistry
- Helps chemists generate and screen novel chemical libraries of large size and quality
- Bridges interdisciplinary areas of DNA-encoded combinatorial chemistry – synthetic and analytical chemistry, molecular biology, informatics, and biochemistry
- Shows medicinal and pharmaceutical chemists how to efficiently broaden available “chemical space” for drug discovery
- Provides expert and up-to-date summary of reported literature for DNA-encoded and DNA-directed chemistry technology and methods
Informazioni bibliografiche
- Titolo del Libro in lingua: A Handbook for Dna-encoded Chemistry
- Sottotitolo: Theory and Applications for Exploring Chemical Space and Drug Discovery
- Lingua: English
- Autore: Goodnow Robert A. Jr.
- Editore: John Wiley & Sons Inc
- Collana: John Wiley & Sons Inc (Hardcover)
- Data di Pubblicazione: 28 Aprile '14
- Genere: SCIENCE
- Argomenti : Combinatorial Chemistry Techniques methods DNA chemical synthesis Drug Discovery methods
- Pagine: 453
- EAN-13: 9781118487686