Immunotoxicology Strategies for Pharmaceutical Safety Assessment

Un libro in lingua di Herzyk Danuta J. (EDT) Bussiere Jeanine L. (EDT) edito da Wiley-Interscience, 2008

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Editors Herzyk (safety assessment, Merck Research Laboratories) and Bussiere (toxicology, Amgen) and 36 co-contributors explore recently introduced systems for immunotoxicology testing and their uses. Topics include an overview of current regulatory expectations for immunotoxicity evaluations of pharmaceuticals, the relationship of preclinical immunotoxicity safety assessments to clinical development, vaccine safety and testing for drug hypersensitivity, nonclinical models for the study of toxic impacts pharmaceuticals can have on the immune system, and a diverse range of methodologies used in immunotoxicology studies. This important reference is intended for practicing toxicologists in the pharmaceutical industry, regulatory and industrial scientists in drug development, and others in related fields. Annotation ©2009 Book News, Inc., Portland, OR (booknews.com)

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