Protein Kinase CK2 - 9780470963036

Protein kinase CK2, one of a large gene family that includes over 500 enzymes, is singled out for study because of its significance in the generation of the human phosphoproteome and for its part in cancer and other disease development. The authors present the variety of work being conducted on this very important enzyme. Topics include: structural basics of protein kinase CK2 function and inhibition, CK2 in embryonic development, CK2 as a global regulator of cell survival, special features, and the role of CK2 in the control of cell plasticity in breast carcinoma progression. It is intended for professionals in fields such as biochemistry, protein science, metabolic regulation, cancer biology, and therapeutics. While the text is very technical, topics are clearly explained, well-illustrated, and extensive references are included. Editor is Pinna (biomedical sciences, U. of Padua, Italy). Annotation ©2013 Book News, Inc., Portland, OR (booknews.com)