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Cellular Mechanotransduction - 9780521895231

Un libro in lingua di Mofrad Mohammad R. K. (EDT) Kamm Roger D. (EDT) edito da Cambridge Univ Pr, 2009

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Mofrad (bioengineering, UC-Berkeley) and Kamm (biomechanics, MIT) present a collection of papers helping to define the field of mechanomics and discussing the many and diverse ways that cellular mechanotransduction is viewed. Featuring 19 chapters written by 36 international researchers, the text is suitable for use in university courses on biomechanics and as a resource for engineers, physicists, and biologists interested in the critical importance of mechanotransduction in cell function and the various ways it might be understood. The authors focus on the fundamental mechanisms by which a cell senses and transduces mechanical force, addressing the factors that activate the range of signaling pathways, ultimately leading to the observed biological response. A sampling of topics: endothelial mechanotransduction, interactions with the extracellular matrix in cellular mechanotransduction, nuclear mechanics and mechanotransduction, mechanotransduction through local autocrine signaling, and micro- and nanoscale force techniques for mechanotransduction. Annotation ©2010 Book News, Inc., Portland, OR (booknews.com)

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