Target Discovery And Validation Reviews And Protocols

Un libro in lingua di Sioud Mouldy (EDT) edito da Springer Verlag, 2006

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These articles address the practical side of the most current methods for efficient translation of discovered targets onto real drugs, with specific emphasis on siRNAs, antisense oligonucleotides and RNA aptamers. This volume covers DNA methylation and histone modification in cancer, "Wnt" signaling, the NG2/HMP proteoglycan, potential targets inspesis, nucleic acid-based aptamers, selecting short-interfering RNA sequences, suppression of apoptosis to the liver, target validation in solid tumors, collagen-induced arthritis, novel opportunities for therapeutic targeting in autoimmune disease, regulatory RNA and treatment options for individual medicine. Annotation ©2007 Book News, Inc., Portland, OR (booknews.com)

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