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Methods in Microarray Normalization - 9781420052787

Un libro in lingua di Stafford Phillip (EDT) edito da Taylor & Francis, 2008

  • € 75.30
  • Il prezzo è variabile in funzione del cambio della valuta d’origine

Focusing primarily on the practical, this gives researchers tools to use in profiling data into accurate trends when using molecular profiling microarrays to compare healthy cells with their diseased counterparts and develop gene-specific treatments. The contributors of these articles explain the use of early normalization techniques for new profiling methods and include strategies for assessing the utility of various normalization algorithms. They include innovations from commerical laboratories as well as normalization methods for protein and other arrays. Topics include a means for comprehensive analysis of the effect of microarray data preprocessing methods on differentially expressed transcript selection, differentiation detection in microarray normalization, spatial de-trending and normalization methods for two-channel DNA and protein microarray data, a survey of cDNA microarray normalization, technical variations in modeling the joint expression of several genes, analysis for certain data normalization, and array-based analysis for the detection of chromosomal aberrations and copy number variations. Annotation ©2008 Book News, Inc., Portland, OR (booknews.com)

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