Cardiovascular Proteomics

Un libro in lingua di Vivanco Fernando (EDT) edito da Springer Verlag, 2006

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Seventy-seven international researchers contribute 31 chapters outlining cutting-edge protocols and strategies for proteomic evaluation of cardiovascular disease. The material is organized into sections addressing the analysis of the heart proteome, heart subproteomes, proteomics of human atheroma plaques, the proteome of cells of the cardiovascular system, cardiovascular biomarkers in plasma, and emerging technologies in bioinformatics. A sampling of topics: two-dimensional polyacrylamide gel electrophoresis for cardiovascular proteomics, subcellular fractionation, optimization of cardiac troponin I pull-down by IDM affinity beads and SELDI, characterization of the human atheroma plaque secretome by proteomic analysis, the proteome of endothelial cells, the proteome and secretome of human arterial smooth muscle cell, isolation of the platelet releasate, cardiovascular biomarker discover by SELDI-TOF mass spectrometry, and techniques to decipher molecular diversity by phage display. Illustrated in b&w. Annotation ©2007 Book News, Inc., Portland, OR (booknews.com)

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