Chemical Biology

Un libro in lingua di Waldmann Herbert (EDT) Janning Petra (EDT) edito da John Wiley & Sons Inc, 2009

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One way of teaching chemical biology--using methods of chemistry to study biological phenomena--is to present in depth separate courses in chemistry, physics, and biology using standard textbooks but complementing them by lecture series, seminars, and practical courses that demonstrate the interplay between the sciences and the corresponding experimental techniques in chemical biology. This case book was designed to be used in that middle complex, detailing successful examples of research to highlight how the combination of sciences can provide new insights into biological phenomena. Among the topics are yeast-based chemical genomic approaches, activity-based protein profiling of cys proteases, using analogue sensitive technologies to target kinases of interest, using split inteins to prepare semi-synthetic proteins and to study the mechanisms of protein trans-splicing, and introducing chemical reporter groups by bio-orthogonal ligation reactions for imaging cell-surface glycans. Annotation ©2010 Book News, Inc., Portland, OR (booknews.com)

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