Nanoparticulate Drug Delivery Systems - 9781118148877

Enthusiasm for nanomedicine has grown exponentially because it addresses critical problems in delivery of some drugs such as poor absorption, toxic side effects, and multiple drug resistance, but challenges remain in translating novel ideas into clinical benefits, e.g, the promise of the active targeting strategy to increase tumor accumulations of nanoparticles has not proved to be a magic bullet. In this state-of-the-art contribution to the field, Yeo (industrial and physical pharmacy, biochemical engineering, Purdue U., Indiana) introduces a dozen chapters reviewing the latest nanomedicine technologies and their preclincial evaluation. Following an overview of targeted nanomedicine, chapters discuss nanoparticulate drug delivery systems that have gained growing recognition, and opportunities and challenges posed by the relevant biology. Includes supporting tables and figures, and extensive references. Annotation ©2013 Book News, Inc., Portland, OR (booknews.com)